Top seed Roger Federer ousted by Tomas Berdych in U.S. Open

Roger Federer wipes his brow late in the fourth set during his loss to Tomas Berdych in the quarterfinal round of play at the U.S. Open. (Sept. 5, 2012)

Roger Federer was knocked out of the US Open with a surprise defeat by sixth seed Tomas Berdych, who will face Andy Murray in the semi-finals on Saturday.

The world number one and five-time champion lost 7-6 (7-1) 6-4 3-6 6-3 in two hours 42 minutes, his first ever quarter-final defeat in New York.

Berdych of the Czech Republic out-hit Federer to reach the last four at Flushing Meadows for the first time.